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[1] The Human Evidence Gap and Where Research Is Heading The most intellectually honest statement about BPC-157 is this: an unusually robust preclinical literature has established a plausible and broadly consistent mechanistic picture, while the human clinical trial evidence remains essentially absent

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At 68 weeks, participants receiving the cagrilintide-semaglutide combination achieved a mean body weight reduction of 22.7% under the trial product estimand