The neurovascular unit The term bloodbrain barrier has a long history, but it has become increasingly recognized that it does not adequately encompass the wide range of morphological features and functional characteristics that it is now known to involve
12 levels
Proline metabolism in cell regulation and cancer biology: recent advances and hypotheses
, 30 , 1324, Su, H., Jiang, M., Senevirathne, C., Aluri, S., Zhang, T., Guo, H., Xavier-Ferrucio, J., Jin, S., Tran, N.-T., Liu, S.-M., Sun, C.-W., Zhu, Y., Zhao, Q., Chen, Y., Cable, L., Shen, Y., Liu, J., Qu, C.-K., Han, X., Klug, C
Researchers should consult the primary literature and follow their institution's biosafety and chemical-handling protocols
Interestingly, the elevated CHAC1 levels in TP53-mutant cells might represent an adaptive response, potentially compensating for defective ferroptosis pathways or preventing harmful GSH accumulation