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This signaling results in the expression of defense-related genes, such as genes involved in SA biosynthesis and encoding WRKY transcription factors 14

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Other signs include digestive issues like diarrhea or constipation, and mouth ulcers

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The rate-limiting step in the de novo synthesis of the GSH is catalyzed by gamma-glutamyl-cysteine synthetase (also known as glutamine-cysteine ligase), which is a target gene of Nrf2

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