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To uncover the underlying mechanisms, the researchers analyzed hippocampal tissue focusing on dentate gyrus, where they quantified neural progenitor proliferation and neurogenesis through BrdU, immunofluorescence for Sox2, GFAP, DCX and NeuN, and unbiased stereological cell counting

doi:10.1159/000450702 96. Pinheiro, J., Bates, D., DebRoy, S., Sarkar, D., Heisterkamp, S., Willigen, B., & Ranke, J

This multifaceted mechanism, targeting both central appetite centers and peripheral glucose control points, makes it a subject of significant interest in metabolic research

In some embodiments, the otic formulation or composition comprises about 0.04% by weight of the silicon dioxide