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Since GSH synthesis contained two ATP-consuming reactions, the supplement of ATP became one of the major factors which affected the GSH production
Abstract Ischemic stroke, a leading cause of global disability and mortality, remains inadequately treated beyond reperfusion, with persistent translational failures in neuroprotection
MassHunter Data Analysis and MassHunter Quantitative Analysis software programs (Agilent Technologies, Barcelona, Spain) were used to collect and quantify the data, respectively
Glutathione works through several mechanisms: The thiol group directly neutralizes free radicals It helps regenerate other essential antioxidants like vitamins C and E It binds with toxins to make them water-soluble for elimination It helps repair DNA damage through enzyme systems This molecular powerhouse balances production, consumption, and recycling to ensure our cells stay protected
doi: 10.1016/j.devcel.2007.12.002