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The body manufactures thousands of them every day to send signals between tissues

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The body then uses vitamin B12 for various functions, In a person with pernicious anemia, the immune system mistakenly attacks the cells that produce the intrinsic factor

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NNMT is an enzyme expressed in adipose tissue, the liver, and other tissues

The sensation you felt after drinking the wine may, or may not, have had anything to do with the B12 but personally I have a tiny (snifter) glass of fortified wine every day without any adverse effect and I'm still " clivealive " and nearly 77 years old Don't forget to get your Folate level checked, Thank you clivealive