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These observations suggest a significant contribution of CYPOR to NFT-induced Nrf2 activation in the HepG2 model, but also indicate that other cellular flavoprotein reductases are likely to be involved in the formation of the NFT radical anion and its subsequent activation of Nrf2 and synthesis of GCLC and glutathione

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siRNA experiments GSTO1 siRNA (Trilencer-27) and scrambled control siRNA were purchased from Origene (Rockville, MD)

Antioxidants help support the bodys natural immune system and toxin-elimination processes

Immunobiology of endometriosis