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These inflammatory signals, in turn, inhibit neuronal mitochondrial biogenesis pathways by downregulating key regulatory factors such as PGC-1 and NRF1/2 (178), thereby impairing mitochondrial turnover and damage repair

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Are Revived Infusions Safe

Tidefelt U, Elmhorn-Rosenborg A, Paul C, Hao XY, Mannervik B, Eriksson LC

doi: 10.2741/4480 201 BelaidiAAMasaldanSSouthonAKalinowskiPAcevedoKAppukuttanATet al

Similarly, IL-6 exhibits context-dependent effects, suppressing osteoblast differentiation in vitro (79) while supporting bone formation in vivo through gp130-mediated pathways (16)