Epimedii Folium decoction ameliorates osteoporosis in mice through NLRP3/caspase-1/IL-1beta signalling pathway and gut-bone axis
Beyond energy conversion, mitochondria are indispensable for a myriad of other cellular processes, including heme and steroid hormone synthesis, calcium ion (Ca 2+ ) buffering to regulate intracellular signaling, and the initiation of apoptosis via the mitochondrial pathway (36)
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In vitro studies using human diploid fibroblast cultures approaching replicative senescence have investigated whether Epithalamin modulates hTERT promoter activity and enzymatic telomerase activity as measured by TRAP assay
Nrf2 belongs to the CNC protein family, including NF-E2 p45, Nrf1, Nrf3, Bach1, and Bach2 (Motohashi et al., 2002)
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