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Histopathological examinations Excised gastric samples were fixed with 10% formalin for one day, dried using ethanol ascending grades, washed in xylol, and then impregnated in soft paraffin for two hours at 50 C before being inserted in hard paraffin blocks

Animal studies administering 5-Amino-1MQ orally to diet-induced obese mice have shown dose-dependent reductions in body weight (typically 10-30% reduction compared to vehicle-treated obese controls over 4-12 week treatment periods), with the weight loss primarily reflecting fat mass reduction while lean mass is preserved or even increased

Effective dosages reported across studies differ

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In contrast, the N -acetylcysteine conjugate was not detected