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Potential mechanisms of action of SSRIs in PCS Dysregulation of the tryptophan system Normally the catabolic kynurenine pathway (KP) degrades 95% of the essential amino acid tryptophan to produce the vital energy cofactor NAD+

Menzel M, Akbarshahi H, Mahmutovic Persson I, Andersson C, Puthia M, Uller L

2017;11(11):Cd000547

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