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An endogenous reductant, NADH, reduces quinone form and semiquinone radical to dihydroxy form, resulting in enhanced generation of reactive oxygen species and DNA damage through the redox cycle

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BMI was found to be negatively linked with serum biotin levels, inflammation, and hypertriglyceridemia in a study involving monozygotic twins who were discordant for BMI (151)

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Acute dopamine depletion model in SD rats This protocol was adapted and modified from McDougall et al