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Conversely, the interplay between the tumor microbiome and host immunity is highly complex, with intratumoral bacteria employing multiple anticancer mechanisms [39, 67,68,69,70]

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Geraghty RJ, Capes-Davis A, Davis JM, Downward J, Freshney RI, Knezevic I, Lovell-Badge R, Masters JR, Meredith J, Stacey GN, Thraves P, Vias M, Cancer Research UK (2014) Guidelines for the use of cell lines in biomedical research

SLC6A14 SLC6A14, also known as amino acid transporter B 0,+ (ATB 0,+ ), maintains a unidirectional influx of glutamine, coupled with 2 Na + and 1 Cl - , along a transmembrane gradient 98

Initiation of pharmacotherapy When appropriate, hepatologists should initiate first-line pharmacologic treatments such as nicotine replacement therapy (NRT), varenicline, or bupropion, all of which have proven efficacy in smoking cessation

L2HG sensitizes HCC cells to ferroptosis through ATF3/CHAC1-mediated GSH degradation