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10.1016/j.crohns.2012.12.006 J

Non-selective c-Met inhibitors include crizotinib (PF-02341066), foretinib (XL-880), cabozantinib (XL-184), glesatinib (MGCD265), BMS-777607, and MK2461, which in addition to c-Met, can inhibit other tyrosine kinases, such as ALK, RON, VEGFR2, KIT, TIE2, PDGFR, VEGFR1, VEGFR3, RET, and FLT-3 [163,164,165], through binding to the ATP binding site on tyrosine kinases

Several authors have suggested [59, 92] that Prx2 can also have an important role in erythropoiesis

Understanding these mechanisms helps clinicians determine whether the elevation is benign or indicative of significant pathology

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