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Cell Biochem Funct 34:620627 Fahey RC, Brown WC, Adams WB et al (1978) Occurrence of glutathione in bacteria

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The most potent inhibitor of TGR, however, was a gold-containing complex called auranofin, low levels of which inhibited TGR in test tubes, completely killed larval, juvenile, and adult parasites living in laboratory dishes within hours, and more than halved the worm burden in infected mice

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Mutation of cysteine 26 alone or in combination with mutation of other cysteines increases GLRX deglutathionylation activity We next investigated the deglutathionylating activity of WT GLRX or GLRX Cys-Ser mutants using diE-GSSG (Fig