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Thereby, the endothelium rescue provided by BPC 157 strongly opposes the chain of events that leads to RV failure and normalizes pulmonary arterial hypertension, even if it is already advanced, as we consistently found in experiments

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The GSTF8 gene was also induced by H 2 O 2 through the activation of MPK3/MPK6 kinases (Kovtun et al., 2000) the promoter of which contains an as-1 motif, which is implicated in response to oxidative stress (Garretn et al., 2002)

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