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These effects seem to be mediated by biliverdin and bilirubin (BV/BR) (62, 65)

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It can interfere with JAK signal transduction and STAT signaling pathway by inhibiting the activity of one or more JAKs, and simultaneously inhibit the production of multiple cytokines to reduce inflammation and inflammation-related pain (225, 226)

Regulation of the expression of inducible nitric oxide synthase

Glutathione: Roles in health and disease

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