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In contrast, other groups exhibited significant remodeling, including disorganized collagen, loss of medial layer boundaries and increased elastin fiber fragmentation (Fig

Genetics family history often plays a major role

Promote M2 macrophage polarization (anti-inflammatory, tissue repair phenotype) versus M1 macrophages (pro-inflammatory, tissue damage)

Cuproptosis is a unique form of RCD driven by the cytotoxic accumulation of copper, with its upstream regulation and execution being critically dependent on the mitochondrial reductase FDX1 [53]

Such insights could enhance clinicians understanding of sleep-related disorders and their complications in postmenopausal women, thereby reducing the likelihood of missed diagnoses and delays in clinical intervention

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