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Mechanistically, DM-induced perturbations in the AMPK/mTOR signaling axis, impaired branched-chain amino acid catabolism, and tryptophan-kynurenine axis dysregulation collectively drive oxidative stress and immune homeostasis disruption through cascade reactions, culminating in pulmonary parenchymal injury

Mechanisms of nkt cell anergy induction involve cbl-B-Promoted monoubiquitination of Carma1

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doi: 10.1080/20002297.2022.2053389, 64 LanY.WangX.YanF.ZhangW.ZhaoS.SongY.et al

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Hopkins revealed its physiological significance and narrowed down the chemical composition to glutamate and cysteine, resulting in the name glutathione [122]