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Moreover, as cystine is an extracellular source of cysteine, cystine uptake is facilitated by the efflux of glutamate via the xCT antiporter

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doi: 10.3390/antiox11010167 32 GutteridgeJMHalliwellB

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Regulatory & Medical Community Viewpoint (2025) The leading dermatology and pharmacology reviews caution against parenteral (IV/IM) glutathione for cosmetic skin-lightening citing lack of robust evidence and significant safety concerns