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The best choice depends on the delivery method, individual genetics, and clinical goals

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doi: 10.1016/j.vph.2018.02.010

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Therapy for a severe deficiency: 1000g Supply vs Intake: Not all Vitamin B12 can be Absorbed These rather high dosages are explained through the biological mechanism that enables the body to intake vitamin B12

For individuals experiencing fatigue or low vitamin levels, B12 injections may help support normal energy levels before and during travel