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doi: 10.1038/s42255-021-00516-2 231 TeoAKKWindmuellerRJohanssonBBDiriceENjolstadPRTjoraEet al

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An important pathogenic factor is the chronic gallbladder irritation and inflammation [117, 172]

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In addition, many (though by no means all) long-term benzodiazepine users are constitutionally highly strung, sensitive people with relatively low self-esteem, whose anxiety problems have led to the prescription of benzodiazepines in the first place and whose continuing anxiety (possibly heightened by the benzodiazepines) has prompted the doctor to go on prescribing the drugs

MR scan assessors were blinded to participant group allocation