first reported the dedifferentiation of hepatocytes into fibroblasts via EMT ( Snail and Slug , repressing the mesenchymal program and EMT of hepatocytes ( Hepatocytes could also dedifferentiate into hepatic progenitor cells (HPCs, which are identified by markers such as SMA, SOX9, KRT19, EpCAM, and PROM1), and the proliferation and differentiation of hepatocyte-derived HPCs are closely associated with ductular reactions and portal fibrosis in liver injury ( Mat1a - / - mice transformed into fibroblastic cells when incubated with FGF10 and TGF-1, and these HPC-derived fibroblasts were significantly expanded in RRV-induced BA mouse model ( 9
Treatment Categories for IC/BPS The Panel assessed the available data for each treatment to determine whether a specific intervention demonstrated sufficient efficacy to be included as a treatment alternative
New insights into vitamin K biology with relevance to cancer
As a result, silymarin can be supposed in treating inflammatory anemia in peritoneal dialysis patients (47)
10.1016/j.surg.2012.12.004 Surgery 65 MarsonA.LevineS
This page is a literature-context overview of time-course data reported in the published in-vitro and rodent-model record