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We further demonstrated that these genes are concordantly differentially expressed in previous cross-sectional studies involving larger numbers of individuals with varying degrees of airflow limitation

We then concentrated on the mechanistic findings related to the acceleration of depression in the context of GD, as mounting evidence has indicated that GD promotes the development of depression through various mechanisms, including triggering autoimmune responses, inducing hormonal disorders, and influencing the thyroid-gut-microbiome-brain axis

Growth hormone secretagogues: History, mechanism of action, and clinical development

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Thompson CB

There is no officially safe maximum limit for humans