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ML162 derivatives incorporating a naphthoquinone unit as ferroptosis/apoptosis inducers: design, synthesis, anti-cancer activity, and drug-resistance reversal evaluation
Following a single mild TBI in mice, glucose utilization in the hippocampus and sensorimotor cortex increased in the first 3 days following injury, while rTBI (a second injury 3 days following the first injury) failed to elicit the same immediate response (63)
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However, avoid administering it with strong acid or vitamin C formulations in the same session, as peptides can degrade at low pH
(PubMed) Lloret A, Badia MC, Mora NJ, Pallardo FV, Alonso MD, Vina J