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PMC 6450803

These positive effects suggested the improvement in locomotor, memory and cognitive functions, which may be credited to the depicted abilities of the tested agents to reverse MSG-induced perturbation in glutamate levels, thereby hampering the resultant excitotoxic effects and opposing MSG-mediated alterations in neurotransmitters levels

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V-9302 reduces the growth of PIK3CA -MT colorectal cancer cells when combined with aspirin The alteration of glutamine metabolism is reportedly a novel strategy for cancer therapy in glutamine-dependent hematologic and solid tumors, including PIK3CA -MT colorectal cancer 40,41,42

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In response, glutathione production is stimulated in phase II detoxification