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High peptide purity helps reduce variability in laboratory experiments and improves confidence in research findings

Techniques included MALDI-MSI for ASO visualization and analysis of neurotransmitters, lipids, and proteins, highlighting significant changes in synaptic activity

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Ito et al., 2023) (this may be particularly relevant for the destabilization of myelin), synaptic dysfunction (Tu et al., 2014) (this includes impairment of signaling at the axo-myelinic synapse, crucial for survival of the myelinated axon

Oxidation A chemical reaction in which an amino acid side chain loses electrons