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Intracellular glutathione synthesis depends on adequate cysteine, glycine, and glutamate availabilitynutrients often compromised in inflammatory or malabsorption states

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Levels of liver paraoxonase, arylesterase, ALT, AST, and LDH can serve as indicators to evaluate the degree of liver damage

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(2025) demonstrated that USP2 deletion in mice impairs synchrony among SCN neurons, dampens molecular rhythms, and alters behavioral circadian outputs, reinforcing USP2s role in maintaining coherence within the central clock network (Srikanta et al., 2025)