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Oxidative stress and NRF2/KEAP1/ARE pathway in diabetic kidney disease (DKD): new perspectives

The glutamatergic system expression in human PC-3 and LNCaP prostate cancer cells

Campbell C, Kandalgaonkar MR, Golonka RM, Yeoh BS, Vijay-Kumar M, Saha P

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In primary cortical neuronal cultures from ARE-hPAP mice (E15), tBHQ (tert-butylhydroquinone), a prototypical Nrf2-ARE activator, increased hPAP activity 30 to 50 fold and indicated that the hPAP activity was induced primarily in the astrocyte 21 , 13

"In those with higher IGF-1 [coupled with] poorer health outcomes, this raises the question of what comes first, the elevated IGF-1 level, or a disease state-causing IGF to elevate via a different mechanism," Dr