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Although the body can in principle synthesize L-carnitine from the amino acids lysine and methionine, a deficiency is still possible, especially in situations where there is an increased demand

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In humans, administration of 2 g/day of ALCAR for 50 days increased plasma ALCAR concentrations by 43%, suggesting that either ALCAR was absorbed without prior hydrolysis or that L-carnitine was re-acetylated in the enterocytes (5)

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