3I, J) and JC-1 staining demonstrated a clear recovery of mitochondrial membrane potential alterations induced by Erastin following QCT pre-treatment (Fig
We then evaluated the induction of lipid ROS in the cells to verify the activation of ferroptosis
Li Q, Kannan A, Das A, et al
[DOI] [PubMed] [Google Scholar] 37.Kapoor M.S., DSouza A., Aibani N., Nair S.S., Sandbhor P., Kumari D., Banerjee R
Further, the inherent limitations of studying topical dosing in murine models necessitates further studies of pharmacokinetics and efficacy in larger species, as well as ocular safety and tolerability studies
This accompanied significantly lower TNF- and elastin-degrading MMPs, creating optimal healing environments