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Similarly, a systematic review and meta-analysis evidence shows that even peripheral blood glutamate levels were significantly increased in MDD patients compared to the controls (112)

Subsequent investigation revealed that this enzyme had peptidase activity and lacked the previously ascribed aflatoxin oxidative activity (Karai et al., 2017)

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Additionally, the R152H mutation in GPX4 is involved in the development of Sedaghatian-type spinal metaphyseal dysplasia, a rare and fatal disease in newborn babies

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