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While early nonresponse is considered to be an indicator of later nonresponse and subsequent treatment resistance in schizophrenia [67], to our knowledge, the association between early nonresponse in first-episode samples and later sequential treatment failures and the status of conventionally defined TRS is yet to be established

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This naturally occurring copper complex found in human plasma, saliva and various biological fluids has molecular weights ranging from 340-400 Da depending on copper ions binding state and conformational changes

In terms of completion of the entire trial, 29 participants were treated with a combined treatment of cagrilintide and semaglutide and treatment with semaglutide by itslef while 30 participants were treated with cagrilintide