Clinical trials have shown that NAC can markedly improve the symptoms of schizophrenia, particularly negative symptoms that are often less responsive to conventional antipsychotics (Table I) (217226)
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As reviewed in the previous application, it has been demonstrated in a clinical study that 3 grams of glutathione delivered by oral ingestion does not elevate plasma glutathione levels (Witschi)
N-Acetyl Cysteine (NAC)
Plasma protein carbonyls is another oxidative stress marker that has been found to be increased during manic and depressive phases in patients with bipolar disorder (Andreazza et al
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