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Supplementation with GSH rescues cancer cell survival and growth in cystine-deficient conditions, and this rescue depends on the catabolic activity of -glutamyltransferases

Increased lipid polarity indicates the effect on cell membranes

WT1 has been shown to bind to the IGF-1R promoter and to suppress activity (Werner et al, 1995)

Results The enzyme samples are incubated in a phosphate buffer containing specific concentrations of glutathione (GSH) and peroxide and then incubated for a suitable time to react before Ellman's reagent (5,5-dithiobis-(2-nitrobenzoic acid) (DTNB) is added

Properties 2.1 Density 1.216 at 20 2.2 Boiling Point 196.6 at 101.3kPa 3