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Unfolding of mucins is dependent on concentrations of bicarbonate, calcium, and sodium in the airway with high concentrations of extracellular calcium, acidic pH, or hyperabsorption of sodium preventing unfolding of the gel-forming mucins (Kesimer et al., 2010

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Main Research Findings 1) Intra-articular administration of AOD9604 was shown to improve cartilage regeneration in cases of collagenase-induced knee osteoarthritis

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