Months 3 to 6 The biggest changes happen here
Adverse Reactions/Side Effects In most cases, methylcobalamin is nontoxic, even in large doses
While some patients report improvements in skin clarity or texture after B12 shots, these changes are usually most noticeable when a deficiency existed beforehand
The most common side effect is some soreness at the injection site, and you might notice your urine turning bright yellow (thats just the excess vitamins, particularly riboflavin, being excreted)
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[3] Initial treatment of pernicious anemia typically consists of 1,000 mcg intramuscularly daily for one week, then weekly for four weeks, transitioning to 1,000 mcg monthly for life