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The time delay is due to the reduction of oxidative stress & pigment reduction internally
2016, doi:10.1038/nrdp.2016.8 Liang, Dan et al
10.1002/2211-5463.12402 125 WangC.-K.YangS.-C.HsuS.-C.ChangF.-P.LinY.-T.ChenS.-F.et al (2017)
In another double-blind, placebo-controlled trial, an improvement in cognitive performance (i.e., MMSE score) was reported in AD patients randomized to receive 800 IU/day of all - rac --tocopherol (360 mg/day of RRR --tocopherol) for six months only when the treatment effectively reduced oxidative stress (as assessed by the measure of total glutathione and markers of lipid peroxidation in the blood) (110)
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Cellular energy, mitochondrial function and fatigue NAD+ is the coenzyme that mitochondria the energy factories of every cell depend on to convert food into ATP, the molecular currency of energy
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