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Protective role of metallothionein in acute lung injury induced by bacterial endotoxin

Via this metabolic adaptation, cells can continually generate TCA metabolites, such as -KG and citrate, which are converted to cytosolic acetyl-CoA for lipid biosynthesis (Fig

7 October 2002

These toxins can lead to subtle cellular changes such as interfering with the methylation of DNA (Rooney 2011)