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4.1 Rheumatoid arthritis The pathogenic process of RA, a systemic autoimmune disease characterized by persistent synovitis, involves the activation of an aberrant immune response and the breakdown of immune system tolerance (131)

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[DOI] [PubMed] [Google Scholar] 21.Picano E.D.A., Lopes-Paulo F., Marques R.G., Diestel C.F., Caetano C.E.R., de Souza M.V.M., Moscoso G.M., Pazos H.M.F