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Studies have been published which report that the use of nonsteroidal anti-inflammatory drugs cause a depletion of glutathione levels.[1] ,[2],[3] Commonly used NSAIDs include: ibuprofen (Advil, Motrin, Nuprin), naproxen (Aleve), piroxicam (Feldene) and ketoprofen (Orudis) as well as many prescription strength NSAID

[PubMed] [Google Scholar] Jaeschke H

And there are less, lets say, prolactin and cortisol effects

Komperd MJ, Sommer C, Mellin-Olsen T, Iversen PO, Rseth AG, Valeur J

Further symptoms that can be treated include: neuropsychiatric disturbances which can range from mild to severe, including disorders of speech, cognition (e.g