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and lower affinity coordinating copper by imidazole nitrogen of His sidechain, the amide nitrogens of Val49 and His50 and a water molecule 20

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Serum measurements Mouse serum was detected using mouse E 2 ELISA Kit (#E-90-96), FSH ELISA Kit (#E-86-96), and LH ELISA Kit (# E-85-96) from Genfine Biological Technology Co., Ltd (Beijing, China)