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The most common side effect is minor swelling or redness from the needle used in the injection

Additionally, compared to the tumors of mice without drug treatment and those treated with Ru(II)-OH (64.4%) and NP2 (73.6%), the tumors of mice treated with NP4 (81.2%) exhibited a higher proportion of mature DCs (CD80 + CD86 + ) (Supplementary Fig

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Most of these events were mild to moderate and concentrated in the first four weeks of each dose escalation, meaning they tended to appear (and resolve) each time the dose increased