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This was accompanied by increased expression of Nrf2, antioxidant genes (NQO1, HMOX1, SOD1) and the multidrug resistant transporters (ABCC1, ABCG2, ABCC3)

Taken together, ferroptosis is not only a form of regulated necrotic cell death, but also a potent disruptor of the BBBs anatomical and immunological defenses

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Designed antimicrobial and antitumor peptides with high selectivity