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Copper accumulation also becomes a theoretical concern at extreme doses, though practical protocols stay well below problematic thresholds

Wang C, Su B, Lu S, Han S, Jiang H, Li Z, et al

While diet and an overall healthy lifestyle can help minimize gray hairs, theres only so much that you can do to control the natural loss of melanin in your hair follicles

10.1371/journal.pone.0065205 53 GarretnV.CarpinelliJ.JordanaX.HoluigueL

Huysmans, D

However, significant translational barriers remain: no human pharmacokinetic data, high synthesis cost, unknown long-term safety, and the absence of clinical trials