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Liver and Detox Support Aids in clearing excess lipids from the liver (beneficial for NAFLD) Enhances methylation-based detox of xenobiotics and estrogen metabolites Improves glutathione production and antioxidant capacity 3

through the autocrine or paracrine form to promote self-proliferation (61)

(51) reported that adherence to a plant-based dietary pattern reduced the risk of COPD associated with long-term exposure to PM 2.5 , NO, and NO x

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[38] Ketoconazole can inhibit testosterone secretion at doses of 200-400 mg/day and can inhibit cortisol synthesis in doses of 400-600 mg/day

Educational materials could also be developed to reframe consumer perceptions, teaching people to appreciate bitter or pungent foods (e.g., bitter greens, turmeric, chili peppers) not as unpleasant, but as sources of beneficial, low-dose biological stressors