In fact, MTX therapy reduced the incidence of vascular disease in patients with psoriasis or RA and it was hypothesized that this effect is caused by the drugs anti-inflammatory property [27]
The improved blood flow helps clear inflammatory debris and brings in the building blocks needed for tissue repair
Because they are much smaller than proteins, they can travel easily through the body and plug into specific receptors on your cells to deliver a clear message, such as start repairing this tissue. Because they are so specific, they generally dont interfere with other parts of the body where they arent needed

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Theres a rationale behind the preference, at least on paper
Facelift, neck lift, blepharoplasty: GLOW once daily for three to four weeks