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[DOI] [PubMed] [Google Scholar] 6.Floyd RA, West MS, Eneff KL, Hogsett WE, Tingey DT

The 20S proteasome can degrade oxidatively modified substrates in an ATP-independent manner [51]

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Therefore, the present review aims to systematically dissect the core molecular mechanisms of ferroptosis, elucidate its specific pathogenic roles in cognitive disorders including AD, PD and DACI as well as provide a comprehensive overview of emerging diagnostic biomarkers and therapeutic strategies targeting this cell death pathway

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