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In model 3, the highest quantile of vitamin B2 intake (OR = 0.613

A RCT verified that patients treated with NAC had higher GSH levels in PBMCs, along with upregulated Foxp3 expression and suppressed mTOR activity (lower expression of phosphorylated S6 protein), which ultimately resulted in lower anti-dsDNA antibody titers and SLEDAI scores (Clinicaltrials.gov: NCT00775476) (255)

Animal studies indicate that it can reduce the activity of the enzyme AMP-activated protein kinase (AMPK), which is located in your brains hypothalamus ( When AMPK is more active, it may increase feelings of hunger

That suggests it could be useful as a complementary therapy when these other medications are prescribed

YH and JD: data curation