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Yeast two-hybrid and in vivo studies demonstrate that jet binds to cry in a light-induced manner, and that jet deficiency leads to cry accumulation in fly heads and cultured cells (Peschel et al., 2009)

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These events recruit autophagy adaptors (p62, OPTN, NDP52) that bridge ubiquitinated OMM proteins (VDAC1, MARF, Mfn1/2) to LC3-labeled autophagosomes [30, 31]

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1 Many studies have shown that severely ill people have low glutathione levels, whether their conditions are cancer, AIDS, liver disease, or a chronic condition